PGD (Embryo Biopsy)
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- Introduced 16 years ago, PGD has now been performed in at least 10.000 cycles, with the majority applied for selection and transfer of eploid embryos in assisted reproduction.
- PGD allows the avoidance of birth of children with inherited disease without risk of pregnancy termination.
- PGD improves implantation and pregnancy rates in poor prognosis IVF treatment.
- PGD reduced over four-fold spontaneous abortion in carriers of chromosomal translocations.
- PGD application is currently expanding to testing for late onset disorders and producing HLA matched offspring , as potential donors for siblings requiring HLA identical stem cell transplantation
- PGD provides access to human embryonic stem cell lines with normal and abnormal genotypes, allowing research on the primary disease mechanisms, to develop treatment regiments for genetic disorders, which are unavailable at present.
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