Using Duo Genetic Test Results to Select the Safest Embryo

Duo genetic testing plays a key role in IVF by helping identify and select the healthiest embryo for transfer. If both intended parents or a donor-recipient pair are carriers of the same genetic condition, their embryos may be at risk. With duo test results and PGT-M (Preimplantation Genetic Testing for Monogenic diseases), doctors can choose embryos that are free from inherited genetic disorders — giving you the best chance of a healthy baby.

Using Duo Genetic Test Results for Embryo Selection

What Happens After Duo Genetic Testing?

1. Both partners (or donor-recipient) are tested for carrier status.

2. If a shared carrier status is found, the embryos may be at risk of inheriting the condition.

3. The IVF lab uses PGT-M to genetically test the embryos before implantation.

4. Embryos free of the disease or not affected are selected for transfer.

What Is PGT-M and How Does It Work?

PGT-M is a highly advanced genetic test performed on embryos created during IVF. It allows the clinic to:

• Detect single-gene disorders

• Distinguish affected, carrier, and unaffected embryos

• Only transfer healthy embryos

Process:

• On day 5 or 6 after fertilization, a few cells are biopsied from each embryo (blastocyst stage).

• DNA from the cells is tested in a lab.

• Results show which embryos are safe to transfer and which carry or are affected by the disease.

Why Duo Genetic Test Results Are Critical for PGT-M

Duo testing tells the lab what to look for. Without knowing the genetic mutations both partners or donor-recipient carry, the lab cannot effectively screen the embryos.

Example:

If both the donor and the intended parent are carriers of spinal muscular atrophy (SMA), PGT-M will specifically look for the SMN1 gene mutations in the embryos. This way, embryos affected by SMA can be avoided.

Types of Embryos Identified After PGT-M

Benefits of Combining Duo Genetic Testing with PGT-M

✅ Improves embryo selection accuracy
✅ Reduces risk of inherited disorders
✅ Improves live birth outcomes
✅ Provides confidence and peace of mind
✅ Helps avoid difficult decisions later in pregnancy

When Should You Consider PGT-M After Duo Testing?

• If you and your partner/donor are carriers of the same condition

• If you have a family history of inherited disorders

• If you want to select the safest embryos for transfer

• If you’re pursuing donor egg or sperm IVF and want additional safety

Common Conditions That May Require Embryo Screening

FAQs: Embryo Selection with Duo Test Results

1. Can duo genetic test results help avoid genetic disorders in IVF babies?

Yes, when combined with PGT-M, they guide the lab in selecting embryos not affected by inherited conditions.

2. Is PGT-M only done if there’s a genetic match?

Primarily, yes. It’s recommended when duo testing shows both individuals carry the same gene mutation.

3. Is PGT-M harmful to embryos?

No, it is safe when done in expert labs. Only a few cells are removed, and embryos are not harmed.

4. Can carrier embryos be transferred?

Sometimes, depending on the condition and doctor’s advice, but they may carry risks for future generations.

5. Does embryo testing affect IVF success rates?

It may slightly reduce embryo count, but increases the chance of healthy pregnancy and birth.

Conclusion: Let Genetics Guide You to a Healthier Future

Duo genetic testing and PGT-M give you the power to choose the safest embryo—minimizing risk and maximizing your chances of a healthy baby. Especially in donor IVF, this testing duo ensures smart, science-based decisions for your family’s future.

At IVFTurkey, we combine the latest genetic screening with expert IVF care to help you feel confident every step of the way.

Contact us if you have questions about duo genetic testing, embryo selection, or IVF planning.